Increased surface charge in the protein chaperone Spy enhances its anti-aggregation activity

Chaperones are essential components of the protein homeostasis network. There is a growing interest in optimizing chaperone function, but exactly how to achieve this aim is unclear. Here, using a model chaperone, the bacterial protein Spy, we demonstrate that substitutions that alter the electrostat...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: He, Wei, Zhang, Jiayin, Sachsenhauser, Veronika, Wang, Lili, Bardwell, James C. A., Quan, Shu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573262/
https://ncbi.nlm.nih.gov/pubmed/32817055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012300
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker