Novel TrxR1 Inhibitors Show Potential for Glioma Treatment by Suppressing the Invasion and Sensitizing Glioma Cells to Chemotherapy

Currently, available glioblastoma (GBM) treatment remains ineffective, with relapse after initial response and low survival rate of GBM patients. The reasons behind limited capacities for GBM treatment are high tumor heterogeneity, invasiveness, and occurrence of drug resistance. Therefore, developi...

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Publicat a:Front Mol Biosci
Autors principals: Jovanović, Mirna, Dragoj, Miodrag, Zhukovsky, Daniil, Dar’in, Dmitry, Krasavin, Mikhail, Pešić, Milica, Podolski-Renić, Ana
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Molecular Biosciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573255/
https://ncbi.nlm.nih.gov/pubmed/33134322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.586146
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