Novel TrxR1 Inhibitors Show Potential for Glioma Treatment by Suppressing the Invasion and Sensitizing Glioma Cells to Chemotherapy

Currently, available glioblastoma (GBM) treatment remains ineffective, with relapse after initial response and low survival rate of GBM patients. The reasons behind limited capacities for GBM treatment are high tumor heterogeneity, invasiveness, and occurrence of drug resistance. Therefore, developi...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Jovanović, Mirna, Dragoj, Miodrag, Zhukovsky, Daniil, Dar’in, Dmitry, Krasavin, Mikhail, Pešić, Milica, Podolski-Renić, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573255/
https://ncbi.nlm.nih.gov/pubmed/33134322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.586146
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