Evolutionarily Selected Overexpression of the Cytokine BAFF Enhances Mucosal Immune Response Against P. falciparum

We have previously shown that a variant of the TNFSF13B gene that we called BAFF-var increases the production of the cytokine BAFF, upregulating humoral immunity and increasing the risk for certain autoimmune diseases. In addition, genetic population signatures revealed that BAFF-var was evolutionar...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Lodde, Valeria, Floris, Matteo, Beerman, Isabel, Munk, Rachel, Guha, Rajan, Steri, Maristella, Orrù, Valeria, Abdelmohsen, Kotb, Crompton, Peter D., Gorospe, Myriam, Idda, Maria Laura, Cucca, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573158/
https://ncbi.nlm.nih.gov/pubmed/33123155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.575103
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker