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Gene-Environment Interaction Promotes Alzheimer’s Risk as Revealed by Synergy of Repeated Mild Traumatic Brain Injury and Mouse App Knock-In
There is a strong unmet need for translational progress towards Alzheimer’s disease (AD) modifying therapy. Unfortunately, preclinical modeling of the disease has been disappointing, relying primarily on transgenic mouse overexpression of rare dominant mutations. Clinical manifestation of AD symptom...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Neurobiol Dis |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7572902/ https://ncbi.nlm.nih.gov/pubmed/32858147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105059 |
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