Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate

Acute intoxication with organophosphorus cholinesterase inhibitors (OPs) can trigger seizures that rapidly progress to life-threatening status epilepticus. Diazepam, long considered the standard of care for treating OP-induced seizures, is being replaced by midazolam. Whether midazolam is more effec...

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Gepubliceerd in:Eur J Pharmacol
Hoofdauteurs: Supasai, Suangsuda, González, Eduardo A., Rowland, Douglas J., Hobson, Brad, Bruun, Donald A., Guignet, Michelle A., Soares, Sergio, Singh, Vikrant, Wulff, Heike, Saito, Naomi, Harvey, Danielle J., Lein, Pamela J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572820/
https://ncbi.nlm.nih.gov/pubmed/32898549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2020.173538
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