TSPO PET Using [(18)F]PBR111 Reveals Persistent Neuroinflammation Following Acute Diisopropylfluorophosphate Intoxication in the Rat

Acute intoxication with organophosphates (OPs) can trigger status epilepticus followed by persistent cognitive impairment and/or electroencephalographic abnormalities. Neuroinflammation is widely posited to influence these persistent neurological consequences. However, testing this hypothesis has be...

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Detalles Bibliográficos
Publicado en:Toxicol Sci
Main Authors: Hobson, Brad A, Rowland, Douglas J, Sisó, Sílvia, Guignet, Michelle A, Harmany, Zachary T, Bandara, Suren B, Saito, Naomi, Harvey, Danielle J, Bruun, Donald A, Garbow, Joel R, Chaudhari, Abhijit J, Lein, Pamela J
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Emerging Technologies, Methods, and Models
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657665/
https://ncbi.nlm.nih.gov/pubmed/31087103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz096
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