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Lens fiber cell differentiation occurs independently of Fibroblast Growth Factor Receptor signaling in the absence of Pten

Fibroblast growth factor receptor (FGFR) signaling patterns multiple tissues in both vertebrates and invertebrates, largely through the activation of intracellular kinases. Recent studies have demonstrated that the phosphatase, PTEN negatively regulates FGFR signaling, such that the loss of PTEN can...

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Détails bibliographiques
Publié dans:Dev Biol
Auteurs principaux: Padula, Stephanie L., Sidler, Elaine P., Wagner, Brad D., Manz, Courtney J., Lovicu, Frank J., Robinson, Michael L.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572784/
https://ncbi.nlm.nih.gov/pubmed/32858001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2020.07.017
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