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Metformin and Systemic Metabolism
Metformin can improve patients’ hyperglycemia through significant suppression of hepatic glucose production. However, up to 300 times higher concentrations of metformin accumulate in the intestine than in the circulation, where it alters nutrient metabolism in intestinal epithelial cells and microbi...
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| Publicado no: | Trends Pharmacol Sci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7572679/ https://ncbi.nlm.nih.gov/pubmed/32994049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2020.09.001 |
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