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Metformin: a metabolic modulator

Recent findings have shed new light on the mechanisms of action through which biguanides exert their anti-aging and cytostatic effects in Caenorhabditis elegans and human cell lines. The drop in energy charge resulting from the metformin mediated inhibition of mitochondrial activity affects the func...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pietrocola, Federico, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354711/
https://ncbi.nlm.nih.gov/pubmed/28122334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14794
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