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Structural Biology of Human GPCR Drugs and Endogenous Ligands - Insights from NMR Spectroscopy
G protein-coupled receptors (GPCRs) represent the largest class of “druggable” proteins in the human genome. For more than a decade, crystal structures and, more recently, cryoEM structures of GPCR complexes have provided unprecedented insight into GPCR drug binding and cell signaling. Nevertheless,...
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| 發表在: | Methods |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7572649/ https://ncbi.nlm.nih.gov/pubmed/32911074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2020.08.008 |
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