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Human microbial metabolite mimicry as a strategy to expand the chemical space of potential drugs

The concept of small-molecule mimicry even of weak microbial metabolites present in rodents and humans, as a means to expand drug repertoires, is new. Hitherto, there are few proof-of-concept papers demonstrating utility of this concept. More recently, papers demonstrating mimicry of intestinal micr...

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Détails bibliographiques
Publié dans:Drug Discov Today
Auteurs principaux: Li, Hao, Ranhotra, Harmit S., Mani, Sridhar, Dvořák, Zdeněk, Sokol, Harry, Müller, Rolf
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572573/
https://ncbi.nlm.nih.gov/pubmed/32562605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2020.06.007
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