A journey upstream: Fluctuating platelet-specific genes in cell-free plasma as proof-of-concept for using ribonucleic acid sequencing to improve understanding of postinjury platelet biology

BACKGROUND: The mechanisms of aberrant circulating platelet behavior following injury remain unclear. Platelets retain megakaryocyte immature ribonucleic acid (RNA) splicing and protein synthesis machinery to alter their functions based on physiologic signals. We sought to identify fluctuating plate...

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Detalhes bibliográficos
Publicado no:J Trauma Acute Care Surg
Main Authors: Kornblith, Lucy Zumwinkle, Bainton, Cedric M.V., Fields, Alexander T., Matthay, Zachary A., Magid, Nina T., Nunez-Garcia, Brenda, Prakash, Arun, Kurien, Philip A., Callcut, Rachael A., Cohen, Mitchell J., Bainton, Roland J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571783/
https://ncbi.nlm.nih.gov/pubmed/32195992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002681
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