Perhaps It’s Not the Platelet: Ristocetin Uncovers the Potential Role of von Willebrand Factor in Impaired Platelet Aggregation Following Traumatic Brain Injury

BACKGROUND: Injury to the blood brain barrier exposes endothelium rich in von Willebrand factor (vWF) which may play a role in altered platelet aggregation following traumatic brain injury (TBI). Ristocetin is an antimicrobial substance which induces vWF-mediated aggregation of platelets. We examine...

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Publié dans:J Trauma Acute Care Surg
Auteurs principaux: Kornblith, Lucy Z, Robles, Anamaria J, Conroy, Amanda S, Hendrickson, Carolyn M, Calfee, Carolyn S., Fields, Alexander T., Callcut, Rachael A, Cohen, Mitchell J
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202182/
https://ncbi.nlm.nih.gov/pubmed/29985231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002025
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