Examination of a first-in-class bis-dialkylnorspermidine-terphenyl antibiotic in topical formulation against mono and polymicrobial biofilms

Biofilm-impaired tissue is a significant factor in chronic wounds such as diabetic foot ulcers. Most, if not all, anti-biotics in clinical use have been optimized against planktonic phenotypes. In this study, an in vitro assessment was performed to determine the potential efficacy of a first-in-clas...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Miller, Mariël, Rogers, Jeffery C., Badham, Marissa A., Cadenas, Lousili, Brightwell, Eian, Adams, Jacob, Tyler, Cole, Sebahar, Paul R., Haussener, Travis J., Reddy, Hariprasada Reddy Kanna, Looper, Ryan E., Williams, Dustin L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571676/
https://ncbi.nlm.nih.gov/pubmed/33075071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234832
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