Optimized Production of the Allylamine Antifungal “Terbinafine” by Lysinibacillus Isolate MK212927 Using Response Surface Methodology

PURPOSE: We aimed to optimize the factors affecting the production of the allylamine antifungal, terbinafine, by Lysinibacillus isolate MK212927, a natural producer of this broad-spectrum fungicidal compound. METHODS: We employed a central composite design to optimize the five most important variabl...

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Detalhes bibliográficos
Publicado no:Infect Drug Resist
Main Authors: El-Sayed, Sayed E, El-Housseiny, Ghadir S, Abdelaziz, Neveen A, El-Ansary, Mona R, Aboshanab, Khaled M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571585/
https://ncbi.nlm.nih.gov/pubmed/33116681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S267590
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