Polysomy is associated with poor outcome in 1p/19q codeleted oligodendroglial tumors

BACKGROUND: Chromosomal instability is associated with earlier progression in isocitrate dehydrogenase (IDH)–mutated astrocytomas. Here we evaluated the prognostic significance of polysomy in gliomas tested for 1p/19q status. METHODS: We analyzed 412 histologic oligodendroglial tumors with use of 1p...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Chen, Hui, Thomas, Cheddhi, Munoz, Felipe Andres, Alexandrescu, Sanda, Horbinski, Craig M, Olar, Adriana, McGuone, Declan, Camelo-Piragua, Sandra, Wang, Lu, Pentsova, Elena, Phillips, Joanna, Aldape, Kenneth, Chen, Wen, Iafrate, A John, Chi, Andrew S, Zagzag, David, Golfinos, John G, Placantonakis, Dimitris G, Rosenblum, Marc, Ohman-Strickland, Pamela, Hameed, Meera, Snuderl, Matija
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Basic and Translational Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571489/
https://ncbi.nlm.nih.gov/pubmed/31140557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz098
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