Polysomy for chromosomes 1 and 19 predicts earlier recurrence in anaplastic oligodendrogliomas with concurrent 1p/19q loss

PURPOSE: Loss of chromosome arms 1p and 19q is a molecular feature of oligodendroglial tumors characterized by responsiveness to chemotherapy and a favorable prognosis. The purpose of this study was to evaluate the prognostic significance of polysomy of chromosomes 1 and 19 in the setting of 1p/19q...

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Main Authors: Snuderl, Matija, Eichler, April F., Ligon, Keith L., Vu, Quynh U., Silver, Michael, Betensky, Rebecca A., Ligon, Azra H., Wen, Patrick Y., Louis, David N., Iafrate, A. John
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818514/
https://ncbi.nlm.nih.gov/pubmed/19808867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0867
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