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Sarpogrelate and rosuvastatin synergistically ameliorate aortic damage induced by hyperlipidemia in apolipoprotein E-deficient mice

The current study aimed to investigate whether sarpogrelate and rosuvastatin possess anti-arterial injury, and attempted to elucidate the mechanism of action underlying this activity. Sarpogrelate, a 5-hydroxytryptamine type 2A antagonist, is extensively used to prevent arterial thrombosis; however,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Exp Ther Med
Hauptverfasser: Liu, Hongyang, Xu, Siwei, Li, Guihua, Lou, Dayuan, Fu, Xiaodan, Lu, Qin, Hao, Liman, Zhang, Jingsi, Mei, Jiajie, Sui, Zheng, Lou, Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571328/
https://ncbi.nlm.nih.gov/pubmed/33093907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9300
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