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What are the current limits on determination of protonation state using neutron macromolecular crystallography?

The rate of deposition of models determined by neutron diffraction, or a hybrid approach that combines X-ray and neutron diffraction, has increased in recent years. The benefit of neutron diffraction is that hydrogen atom (H) positions are detectable, allowing for the determination of protonation st...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Liebschner, Dorothee, Afonine, Pavel V., Moriarty, Nigel W., Adams, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571246/
https://ncbi.nlm.nih.gov/pubmed/32093835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2020.01.008
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