A Novel Cytotoxic Conjugate Derived from the Natural Product Podophyllotoxin as a Direct-Target Protein Dual Inhibitor

Natural products are the ideal basis for the design of novel efficient molecular entities. Podophyllotoxin, a naturally occurring cyclolignan, is an example of natural product which displays a high versatility from a biological activity point of view. Based on its unique chemical structure, differen...

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Pubblicato in:Molecules
Autori principali: Hernández, Ángela-Patricia, Díez, Paula, García, Pablo A., Pérez-Andrés, Martín, Ortega, Pablo, Jambrina, Pablo G., Díez, David, Castro, María Ángeles, Fuentes, Manuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571232/
https://ncbi.nlm.nih.gov/pubmed/32957517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184258
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