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Cathepsin B-Cleavable Cyclopeptidic Chemotherapeutic Prodrugs

Cyclopeptidic chemotherapeutic prodrugs (cPCPs) are macromolecular protease-sensitive doxorubicin (DOX) prodrugs synthesized from a cyclodecapeptidic scaffold, termed Regioselectively Addressable Functionalized Template (RAFT). In order to increase the chemotherapeutic potential of DOX and limit its...

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Dades bibliogràfiques
Publicat a:Molecules
Autors principals: Herceg, Viktorija, Bouilloux, Jordan, Janikowska, Karolina, Allémann, Eric, Lange, Norbert
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570921/
https://ncbi.nlm.nih.gov/pubmed/32962018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184285
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