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Downregulation of Inflammatory Cytokine Release from IL-1β and LPS-Stimulated PBMC Orchestrated by ST2825, a MyD88 Dimerisation Inhibitor

The inflammatory process implicates homeostasis disruption and increased production of inflammatory mediators. Myeloid differentiation primary response 88 (MyD88) is an essential protein recruited after lipopolysaccharide (LPS) and interleukin (IL)-1β stimulation, a process that converges in nuclear...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ramírez-Pérez, Sergio, Hernández-Palma, Luis Alexis, Oregon-Romero, Edith, Anaya-Macías, Brian Uriel, García-Arellano, Samuel, González-Estevez, Guillermo, Muñoz-Valle, José Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570868/
https://ncbi.nlm.nih.gov/pubmed/32967164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184322
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