MyD88-dependent Dendritic and Epithelial Cell Crosstalk Orchestrates Immune Responses to Allergens

Sensitization to inhaled allergens is dependent on activation of conventional dendritic cells (cDCs) and on the adaptor molecule, MyD88. However, many cell types in the lung express Myd88, and it is unclear how signaling in these different cell types reprograms cDCs and leads to allergic inflammatio...

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Bibliographic Details
Published in:Mucosal Immunol
Main Authors: Thomas, Seddon Y., Whitehead, Gregory S., Takaku, Motoki, Ward, James M., Xu, Xiaojiang, Nakano, Keiko, Lyons-Cohen, Miranda R., Nakano, Hideki, Gowdy, Kymberly M., Wade, Paul A., Cook, Donald N.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918466/
https://ncbi.nlm.nih.gov/pubmed/29067999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2017.84
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