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Photocontrolled miR-148b nanoparticles cause apoptosis, inflammation and regression of Ras induced epidermal squamous cell carcinomas in mice

Despite evidence that microRNAs (miRNAs) are essential in modulating tumorigenesis, a major challenge in cancer treatment is to achieve tumor-specific selectivity and efficient yet safe delivery of miRNAs in vivo. In this study, we have developed a light-inducible silver nanoparticle nucleic acid de...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Liu, Yiming, Bailey, Jacob T., Abu-Laban, Mohammad, Li, Shue, Chen, Cong, Glick, Adam B., Hayes, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570449/
https://ncbi.nlm.nih.gov/pubmed/32736169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120212
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