MiR-148a impairs Ras/ERK signaling in B lymphocytes by targeting SOS proteins

Although microRNAs have been recognized as central cellular regulators, there is an evident lack of knowledge about their targets. Here, we analyzed potential target genes for miR-148a functioning in Ras signaling in B cells, including SOS1 and SOS2. A dual-luciferase reporter assay showed significa...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Alles, Julia, Ludwig, Nicole, Rheinheimer, Stefanie, Leidinger, Petra, Grässer, Friedrich A., Keller, Andreas, Meese, Eckart
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593572/
https://ncbi.nlm.nih.gov/pubmed/28915601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17662
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