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Location Bias as Emerging Paradigm in GPCR Biology and Drug Discovery

GPCRs are the largest receptor family that are involved in virtually all biological processes. Pharmacologically, they are highly druggable targets, as they cover more than 40% of all drugs in the market. Our knowledge of biased signaling provided insight into pharmacology vastly improving drug desi...

詳細記述

保存先:
書誌詳細
出版年:iScience
主要な著者: Mohammad Nezhady, Mohammad Ali, Rivera, José Carlos, Chemtob, Sylvain
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569339/
https://ncbi.nlm.nih.gov/pubmed/33103080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101643
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