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Effects of the α-2 Adrenergic Receptor Agonists Lofexidine and Guanfacine on Food-Cocaine Choice in Socially Housed Cynomolgus Monkeys

Although norepinephrine (NE) does not appear to play a prominent role in mediating the abuse-related effects of cocaine, studies have indicated that NE α-2 receptor agonists can attenuate reinstatement of extinguished cocaine self-administration in rats and monkeys and can decrease cocaine craving i...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Czoty, Paul W., Nader, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569305/
https://ncbi.nlm.nih.gov/pubmed/32636208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.266007
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