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Differential Effects of Acute and Chronic Treatment with the α(2)-Adrenergic Agonist, Lofexidine, on Cocaine Self-Administration in Rhesus Monkeys
BACKGROUND: Lofexidine, an α(2)-adrenergic agonist, is being investigated as a treatment for reducing opioid withdrawal symptoms and blocking stress-induced relapse to cocaine taking. Opioid abusers are often polydrug abusers and cocaine is one frequent drug of choice. However, relatively little is...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818349/ https://ncbi.nlm.nih.gov/pubmed/23998378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2013.07.032 |
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