Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis

BACKGROUND: Podocyte injury plays an important role in diabetic nephropathy (DN). The aim of this study was to determine the potential therapeutic effects of the ginsenoside Rg1 on hyperlipidemia-stressed podocytes and elucidate the underlying mechanisms. METHODS: In vitro and in vivo models of DN w...

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Pubblicato in:Evid Based Complement Alternat Med
Autori principali: Wang, Tao, Gao, Yanbin, Yue, Rongchuan, Wang, Xiaolei, Shi, Yimin, Xu, Jiayi, Wu, Bingjie, Li, Yimeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568787/
https://ncbi.nlm.nih.gov/pubmed/33133213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2735714
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