Synergy between 15-lipoxygenase and secreted PLA(2) promotes inflammation by formation of TLR4 agonists from extracellular vesicles

Damage-associated endogenous molecules induce innate immune response, thus making sterile inflammation medically relevant. Stress-derived extracellular vesicles (stressEVs) released during oxidative stress conditions were previously found to activate Toll-like receptor 4 (TLR4), resulting in express...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Ha, Van Thai, Lainšček, Duško, Gesslbauer, Bernd, Jarc-Jovičić, Eva, Hyötyläinen, Tuulia, Ilc, Nejc, Lakota, Katja, Tomšič, Matija, van de Loo, Fons A. J., Bochkov, Valery, Petan, Toni, Jerala, Roman, Manček-Keber, Mateja
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568244/
https://ncbi.nlm.nih.gov/pubmed/32973091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005111117
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares