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Synthesis, density functional theory (DFT) studies and urease inhibition activity of chiral benzimidazoles

A variety of benzimidazole by the heterocyclization of orthophenylenediamine were synthesized in 69–86% yields. The synthesized compounds 3a-f and 6a-f were characterized and further investigated as jack bean urease inhibitors. Density functional theory (DFT) studies were performed utilizing the bas...

詳細記述

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書誌詳細
出版年:Heliyon
主要な著者: Aman, Hasil, Rashid, Naghmana, Ashraf, Zaman, Bibi, Aamna, Chen, Hsin-Tsung, Sathishkumar, Nadaraj
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567930/
https://ncbi.nlm.nih.gov/pubmed/33088954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e05187
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