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Synthesis, density functional theory study and in vitro antimicrobial evaluation of new benzimidazole Mannich bases

The tri-component synthesis of novel chiral benzimidazole Mannich bases, by reaction between benzimidazole, aqueous 30% formaldehyde and an amine, the biological evaluation and DFT studies of the new compounds are reported here. The (1)H-NMR, (13)C-NMR, FTIR spectra and elemental analysis confirm th...

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Библиографические подробности
Опубликовано в: :BMC Chem
Главные авторы: Marinescu, Maria, Cinteză, Ludmila Otilia, Marton, George Iuliu, Chifiriuc, Mariana-Carmen, Popa, Marcela, Stănculescu, Ioana, Zălaru, Christina-Marie, Stavarache, Cristina-Elena
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382033/
https://ncbi.nlm.nih.gov/pubmed/32724899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-020-00697-z
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