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Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation

Kaposi’s sarcoma herpesvirus (KSHV) is an oncogenic human virus and the leading cause of mortality in HIV infection. KSHV reactivation from latent- to lytic-stage infection initiates a cascade of viral gene expression. Here we show how these changes remodel the host cell proteome to enable viral rep...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Gabaev, Ildar, Williamson, James C., Crozier, Thomas W.M., Schulz, Thomas F., Lehner, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567700/
https://ncbi.nlm.nih.gov/pubmed/33053346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108249
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