Cargando...
Toward structure-based drug design against the epidermal growth factor receptor (EGFR)
Most of the available crystal structures of epidermal growth factor receptor (EGFR) kinase domain, bound to drug inhibitors, originated from ligand-based drug design studies. Here, we used variations in 110 crystal structures to assemble eight distinct families highlighting the C-helix orientation i...
Guardado en:
| Publicado en: | Drug Discov Today |
|---|---|
| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier Ltd.
2020
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7567673/ https://ncbi.nlm.nih.gov/pubmed/33075469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2020.10.007 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|