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Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila

Neuroregeneration is a dynamic process synergizing the functional outcomes of multiple signaling circuits. Channelrhodopsin-based optogenetics shows the feasibility of stimulating neural repair but does not pin down specific signaling cascades. Here, we utilized optogenetic systems, optoRaf and opto...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Wang, Qin, Fan, Huaxun, Li, Feng, Skeeters, Savanna S, Krishnamurthy, Vishnu V, Song, Yuanquan, Zhang, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567606/
https://ncbi.nlm.nih.gov/pubmed/33021199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57395
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