FGF13 Is a Novel Regulator of NF-κB and Potentiates Pathological Cardiac Hypertrophy

FGF13 is an intracellular FGF factor. Its role in cardiomyopathies has been rarely investigated. We revealed that endogenous FGF13 is up-regulated in cardiac hypertrophy accompanied by increased nuclear localization. The upregulation of FGF13 plays a deteriorating role both in hypertrophic cardiomyo...

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Udgivet i:iScience
Main Authors: Sun, Jia, Niu, Chao, Ye, Weijian, An, Ning, Chen, Gen, Huang, Xiaozhong, Wang, Jianan, Chen, Xixi, Shen, Yingjie, Huang, Shuai, Wang, Ying, Wang, Xu, Wang, Yang, Jin, Litai, Cong, Weitao, Li, Xiaokun
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567043/
https://ncbi.nlm.nih.gov/pubmed/33089113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101627
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