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Mutation Load of Single, Large-Scale Deletions of mtDNA in Mitotic and Postmitotic Tissues
It is generally accepted that patients with chronic progressive ophthalmoplegia caused by single large-scale deletion (SLD) of mitochondrial DNA (mtDNA) only harbor mutation in skeletal and eye muscles. The aim of this study was to investigate the presence and the level of heteroplasmy of mtDNA dele...
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| Publicado no: | Front Genet |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566915/ https://ncbi.nlm.nih.gov/pubmed/33133144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.547638 |
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