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Design, synthesis, and biological evaluation of N-arylpiperazine derivatives as interferon inducers
Type I Interferon (IFN) signaling plays an important role in the immune defense system against virus infection and in the innate immune response, thus IFNs are widely used as anti-viral agents and treatment for immune disorder or cancer. However, there is a growing demand for novel small-molecule IF...
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| Publicado en: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier Ltd.
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566768/ https://ncbi.nlm.nih.gov/pubmed/33075488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127613 |
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