Targeting the gut to prevent sepsis from a cutaneous burn

Severe burn injury induces gut barrier dysfunction and subsequently a profound systemic inflammatory response. In the present study, we examined the role of the small intestinal brush border enzyme, intestinal alkaline phosphatase (IAP), in preserving gut barrier function and preventing systemic inf...

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Vydáno v:JCI Insight
Hlavní autoři: Adiliaghdam, Fatemeh, Cavallaro, Paul, Mohad, Vidisha, Almpani, Marianna, Kühn, Florian, Gharedaghi, Mohammad Hadi, Najibi, Mehran, Rahme, Laurence G., Hodin, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566703/
https://ncbi.nlm.nih.gov/pubmed/33004693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137128
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