Stress-induced RNA–chromatin interactions promote endothelial dysfunction

Chromatin-associated RNA (caRNA) has been proposed as a type of epigenomic modifier. Here, we test whether environmental stress can induce cellular dysfunction through modulating RNA-chromatin interactions. We induce endothelial cell (EC) dysfunction with high glucose and TNFα (H + T), that mimic th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Calandrelli, Riccardo, Xu, Lixia, Luo, Yingjun, Wu, Weixin, Fan, Xiaochen, Nguyen, Tri, Chen, Chien-Ju, Sriram, Kiran, Tang, Xiaofang, Burns, Andrew B., Natarajan, Rama, Chen, Zhen Bouman, Zhong, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566596/
https://ncbi.nlm.nih.gov/pubmed/33060583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18957-w
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados