Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing

MicroRNA expression is important for gene regulation and deregulated microRNA expression is often observed in diseases such as cancer. The processing of primary microRNA transcripts is an important regulatory step in microRNA biogenesis. Due to low expression level and association with chromatin, pr...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Conrad, Thomas, Ntini, Evgenia, Lang, Benjamin, Cozzuto, Luca, Andersen, Jesper B., Marquardt, Jens U., Ponomarenko, Julia, Tartaglia, Gian Gaetano, Vang Ørom, Ulf A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
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Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566579/
https://ncbi.nlm.nih.gov/pubmed/32669295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.076240.120
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