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UPF2 leads to degradation of dendritically-targeted mRNAs to regulate synaptic plasticity and cognitive function
Synaptic plasticity requires a tight control of mRNA levels in dendrites. Consistently, RNA translation and degradation pathways have been recently linked to neurodevelopmental and neuropsychiatric diseases, suggesting a role for RNA regulation in synaptic plasticity and cognition. While the local t...
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| Pubblicato in: | Mol Psychiatry |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566522/ https://ncbi.nlm.nih.gov/pubmed/31636381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0547-5 |
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