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Antioxidant Apigenin Relieves Age-Related Muscle Atrophy by Inhibiting Oxidative Stress and Hyperactive Mitophagy and Apoptosis in Skeletal Muscle of Mice

Skeletal muscle atrophy in the aged causes loss in muscle mass and functions. Naturally occurring antioxidant flavonoid apigenin is able to ameliorate obesity- and denervation-induced muscle atrophies, but its effects on age-related muscle atrophy remain unknown. We hypothesized that apigenin can re...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Wang, Dongtao, Yang, Yajun, Zou, Xiaohu, Zhang, Jing, Zheng, Zena, Wang, Ziwei
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566467/
https://ncbi.nlm.nih.gov/pubmed/32857105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glaa214
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