1-[(4-Nitrophenyl)sulfonyl]-4-phenylpiperazine treatment after brain irradiation preserves cognitive function in mice

BACKGROUND: Normal tissue toxicity is an inevitable consequence of primary or secondary brain tumor radiotherapy. Cranial irradiation commonly leads to neurocognitive deficits that manifest months or years after treatment. Mechanistically, radiation-induced loss of neural stem/progenitor cells, neur...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Bhat, Kruttika, Medina, Paul, He, Ling, Zhang, Le, Saki, Mohammad, Ioannidis, Angeliki, Nguyen, Nhan T, Sodhi, Sirajbir S, Sung, David, Magyar, Clara E, Liau, Linda M, Kornblum, Harley I, Pajonk, Frank
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566405/
https://ncbi.nlm.nih.gov/pubmed/32291451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa095
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