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Effects of Brain Irradiation in Immune-Competent and Immune-Compromised Mouse Models
Patient-derived orthotopic xenografts (PDOXs) closely recapitulate primary human glioblastoma (GBM) tumors in terms of histology and genotype. Compared to other mouse strains, NOD-scid IL2Rgamma(null) (NSG) mice show excellent tumor take rates, which makes them an ideal host for PDOXs. However, NSG...
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| Udgivet i: | Radiat Res |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7135898/ https://ncbi.nlm.nih.gov/pubmed/31774721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR15373.1 |
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