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Effects of Brain Irradiation in Immune-Competent and Immune-Compromised Mouse Models

Patient-derived orthotopic xenografts (PDOXs) closely recapitulate primary human glioblastoma (GBM) tumors in terms of histology and genotype. Compared to other mouse strains, NOD-scid IL2Rgamma(null) (NSG) mice show excellent tumor take rates, which makes them an ideal host for PDOXs. However, NSG...

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Bibliografiske detaljer
Udgivet i:Radiat Res
Main Authors: Saki, Mohammad, Bhat, Kruttika, Sodhi, Sirajbir S., Nguyen, Nhan T., Kornblum, Harley I., Pajonk, Frank
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7135898/
https://ncbi.nlm.nih.gov/pubmed/31774721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR15373.1
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