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Prkar1a haploinsufficiency ameliorates the growth hormone excess phenotype in Aip-deficient mice

Mutations of the regulatory subunit (PRKAR1A) of the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA), leading to activation of the PKA pathway, are the genetic cause of Carney complex which is frequently accompanied by somatotroph tumors. Aryl hydrocarbon receptor-interacting pr...

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Bibliografski detalji
Izdano u:Hum Mol Genet
Glavni autori: Schernthaner-Reiter, Marie Helene, Trivellin, Giampaolo, Roetzer, Thomas, Hainfellner, Johannes A, Starost, Matthew F, Stratakis, Constantine A
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566352/
https://ncbi.nlm.nih.gov/pubmed/32821937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa178
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