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Regeneration of Tumor-Antigen-Specific Cytotoxic T Lymphocytes from iPSCs Transduced with Exogenous TCR Genes
In the current adoptive T cell therapy, T cells from a patient are given back to that patient after ex vivo activation, expansion, or genetic manipulation. However, such strategy depends on the quality of the patient’s T cells, sometimes leading to treatment failure. It would therefore be ideal to u...
Zapisane w:
| Wydane w: | Mol Ther Methods Clin Dev |
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| Główni autorzy: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Gene & Cell Therapy
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566080/ https://ncbi.nlm.nih.gov/pubmed/33102617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.09.011 |
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