Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters

A series of four water-soluble salicylaldehyde thiosemicarbazones with a positively charged trimethylammonium moiety ([H(2)L(R)]Cl, R = H, Me, Et, Ph) and four copper(II) complexes [Cu(HL(R))Cl]Cl (1–4) were synthesised with the aim to study (i) their antiproliferative activity in cancer cells and,...

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Publicado no:Biomolecules
Main Authors: Milunović, Miljan N. M., Palamarciuc, Oleg, Sirbu, Angela, Shova, Sergiu, Dumitrescu, Dan, Dvoranová, Dana, Rapta, Peter, Petrasheuskaya, Tatsiana V., Enyedy, Eva A., Spengler, Gabriella, Ilic, Marija, Sitte, Harald H., Lubec, Gert, Arion, Vladimir B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565988/
https://ncbi.nlm.nih.gov/pubmed/32825480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091213
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