Ionocytes and CFTR Chloride Channel Expression in Normal and Cystic Fibrosis Nasal and Bronchial Epithelial Cells

The airway epithelium contains ionocytes, a rare cell type with high expression of Forkhead Box I1 (FOXI1) transcription factor and Cystic Fibrosis Transmembrane conductance Regulator (CFTR), a chloride channel that is defective in cystic fibrosis (CF). Our aim was to verify if ionocyte development...

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Published in:Cells
Main Authors: Scudieri, Paolo, Musante, Ilaria, Venturini, Arianna, Guidone, Daniela, Genovese, Michele, Cresta, Federico, Caci, Emanuela, Palleschi, Alessandro, Poeta, Marco, Santamaria, Francesca, Ciciriello, Fabiana, Lucidi, Vincenzina, Galietta, Luis J. V.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565890/
https://ncbi.nlm.nih.gov/pubmed/32933106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9092090
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